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VP, U.S. Medical Affairs

Dynetherapeutics · Waltham, MA · 2026-07-01

executive
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About this role

<div class="content-intro"><h3>Company Overview:</h3> <p>Dyne Therapeutics is focused on delivering functional improvement for people living with genetically driven neuromuscular diseases. We are developing therapeutics that target muscle and the central nervous system (CNS) to address the root cause of disease. The company is advancing clinical programs for Duchenne muscular dystrophy (DMD) and myotonic dystrophy type 1 (DM1) as well as a preclinical programs for facioscapulohumeral muscular dystrophy (FSHD) and Pompe disease. At Dyne, we are on a mission to deliver functional improvement for individuals, families and communities. Learn more at <a href="https://www.dyne-tx.com/">https://www.dyne-tx.com/</a>, and follow us on <a href="https://x.com/dyne_tx">X</a>, <a href="https://www.linkedin.com/company/dynetx/">LinkedIn</a> and <a href="https://www.facebook.com/DyneTherapeutic/">Facebook</a>.</p></div><p><strong>Role Summary:</strong></p> <p><span data-contrast="auto"><span data-ccp-parastyle="Normal (Web)">The VP, U</span><span data-ccp-parastyle="Normal (Web)">.</span><span data-ccp-parastyle="Normal (Web)">S</span><span data-ccp-parastyle="Normal (Web)">.</span><span data-ccp-parastyle="Normal (Web)"> Medical Affairs is </span><span data-ccp-parastyle="Normal (Web)">the senior U.S.</span><span data-ccp-parastyle="Normal (Web)"> </span><span data-ccp-parastyle="Normal (Web)">medical leader with </span><span data-ccp-parastyle="Normal (Web)">end-to-end</span><span data-ccp-parastyle="Normal (Web)"> </span><span data-ccp-parastyle="Normal (Web)">accountability for U.S. medical launch readiness, execution, and early commercialization success for Dyne’s first approved product. This role </span><span data-ccp-parastyle="Normal (Web)">will continue to build</span><span data-ccp-parastyle="Normal (Web)">, </span><span data-ccp-parastyle="Normal (Web)">lead</span><span data-ccp-parastyle="Normal (Web)">, and scale</span><span data-ccp-parastyle="Normal (Web)"> a high-impact U.S</span><span data-ccp-parastyle="Normal (Web)">.</span><span data-ccp-parastyle="Normal (Web)"> Medical Affairs organization</span><span data-ccp-parastyle="Normal (Web)"> and serve as a critical leader</span><span data-ccp-parastyle="Normal (Web)"> capable of delivering excellence in a first-launch, </span><span data-ccp-parastyle="Normal (Web)">high</span></span>‑<span data-contrast="auto"><span data-ccp-parastyle="Normal (Web)">visibility</span><span data-ccp-parastyle="Normal (Web)"> environment.</span></span><span data-ccp-props="{"134233117":true,"134233118":true,"134245417":true}"> </span></p> <p><span data-contrast="auto"><span data-ccp-parastyle="Normal (Web)">This position plays a critical leadership role in shaping Dyne’s transition from a clinical-stage to a commercial-stage company, serving as a core member of cross-functional launch governance and a </span><span data-ccp-parastyle="Normal (Web)">trusted strategic advisor</span><span data-ccp-parastyle="Normal (Web)"> to </span><span data-ccp-parastyle="Normal (Web)">e</span><span data-ccp-parastyle="Normal (Web)">xecutive </span><span data-ccp-parastyle="Normal (Web)">l</span><span data-ccp-parastyle="Normal (Web)">eadership</span><span data-ccp-parastyle="Normal (Web)"> and member of the US Leadership Team (USLT)</span><span data-ccp-parastyle="Normal (Web)">. The VP is accountable for defining and executing the U.S. medical strategy, ensuring scientific and medical excellence, mitigating medical risk, and driving impactful engagement with U.S. healthcare providers, payers, patient communities, and other external stakeholders.</span></span><span data-ccp-props="{"134233117":true,"134233118":true,"134245417":true}"> </span></p> <p><span data-contrast="auto"><span data-ccp-parastyle="Normal (Web)">The VP, U</span><span data-ccp-parastyle="Normal (Web)">.</span><span data-ccp-parastyle="Normal (Web)">S</span><span data-ccp-parastyle="Normal (Web)">.</span><span data-ccp-parastyle="Normal (Web)"> Medical Affairs is a key member of the Global Medical Affairs Leadership Team and works in close collaboration with Global Medical Affairs, Commercial, Market Access, Clinical Development, Regulatory, and other functions to ensure seamless alignment and execution through approval, launch, and early lifecycle management.</span><span data-ccp-parastyle="Normal (Web)"> </span><span data-ccp-parastyle="Normal (Web)">This is a unique opportunity to define and lead the U.S. medical strategy for Dyne’s first commercial…

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