Executive Director, US Brand Lead – Oncology Biosimilars

About this role

Job Title: Executive Director, US Brand Lead – Oncology Biosimilars Job Location: Thousand Oaks, California, United States Job Location Type: Remote Job Contract Type: Full time Job Seniority Level: Join Amgen’s Mission of Serving Patients At Amgen, if you feel like you are a part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do. Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity-related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career. What you will do Let’s do this. Let’s change the world. In this vital role the Executive Director, US Brand Lead for ABP 206 & ABP 234 is accountable for leading the US commercial market readiness strategy for two of Amgen's highest priority oncology biosimilars assets. This leader serves as the single-point commercial owner responsible for building a team and designing and delivering an integrated commercial strategy that prepares the organization for successful market entry while positioning both brands for long-term growth and sustained market leadership. Success in this role requires a seasoned commercial executive preferably with deep expertise in oncology, biosimilar commercialization, market readiness planning, market shaping, and enterprise leadership. Working across a highly matrixed organization, the Executive Director will align Global and US teams around a common vision, establish governance and execution discipline, and ensure every commercial function is prepared to deliver exceptional customer and patient outcomes upon regulatory approval. As a member of the Oncology Business Unit Senior Leadership Team (OBU SLT), this leader will help shape the broader US Oncology commercial strategy, organizational culture, operating model, and long-term growth agenda while serving as a trusted advisor to senior leadership on biosimilar strategy and commercialization. Key Responsibilities include: US Commercial Market Readiness Strategy

Own the comprehensive US commercial market readiness strategy for ABP 206 and ABP 234, ensuring the organization is prepared for successful market entry.

Define the commercial ambition, strategic priorities, success metrics, and critical milestones across both assets

Lead integrated market readiness planning across Marketing, Sales, Medical, Market Access, Patient Support, Digital, Regulatory, Corporate Affairs, Operations, and other key functions

Establish governance, decision-making processes, execution discipline, and accountability across a highly matrixed organization

Lead commercial scenario planning and proactively identify risks and mitigation strategies across regulatory, competitive, access, reimbursement, contracting, and supply considerations

Commercial Strategy & Market Leadership

Define the US commercial opportunity by identifying target patient populations, treatment settings, customer segments, and key decision-makers

Serve as Amgen's commercial authority on the evolving biosimilar marketplace, competitive dynamics, customer behaviors, treatment pathways, and market trends

Identify unmet customer needs, barriers to adoption, and market opportunities that inform differentiated commercial strategies and accelerate market readiness

Translate complex market insights into clear commercial priorities that position both assets for long-term success

Brand Strategy, Positioning & Market Shaping

Lead development of differentiated US brand strategies, positioning, value propositions, and long-term growth narratives for both assets

Partner closely with the Biosimilar Business Unit to shape worldwide strategy while ensuring execution reflects the unique needs of the US oncology marketplace

Develop compelling, evidence-based messaging that resonates across healthcare providers, health systems, payers, patients, and internal stakeholders

Lead market-shaping initiatives that prepare customers and stakeholders for the introduction of both assets while supporting appropriate adoption and access

Commercial Planning & Business Leadership

Lead integrated commercial planning across both brands, including strategic planning, investment prioritization, forecasting assumptions, resource allocation, and performance objectives

Drive execution through disciplined milestone management, executive reporting, and cross-functional performance reviews

Monitor market dynamics and adjust commercial strategies to respond to changing customer needs, competitive actions, reimbursement environments, and regulatory developments

Partner with Finance and Commercial Operations to support forecasting, business planning, and resource optimization

Cross-Functional Leadership & Enterprise Collaboration

Lead a highly integrated cross-functional team spanning Marketing, Sales, Medical, Market Access, Value & Evidence, Digital, Corporate Affairs, Patient Support, Operations, and Global Commercial

Build strong partnerships across the enterprise to ensure alignment, rapid decision-making, and execution excellence

Influence enterprise priorities while representing the commercial perspective across governance forums and senior leadership discussions

Ensure strong integration between Global and…