Sr/Exec Director Clinical Development

About this role

Erasca is a clinical-stage precision oncology company focused on discovering, developing and commercializing medicines for the benefit of patients with cancer. Our programs take novel approaches to shutting down one of cancer’s most commonly mutated signaling cascades, the RAS/MAPK pathway, which affects approximately 5.5 million lives each year worldwide. The name “Erasca” has an important embedded meaning: it is a contraction of our audacious hope to “erase cancer” that drives our mission and everything that we do on behalf of patients with cancer.

Position Summary:

Reporting to the Chief Medical Officer, the Senior or Executive Director, Clinical Development will drive the clinical aspects of late-stage clinical development studies or programs. This person will work closely with cross-functional teams in the management and execution of the Clinical Development Plan (CDP), in developing innovative and efficient solutions to medical and scientific clinical trial issues, and in ensuring the successful execution and completion of clinical trials. The Senior or Executive Director, Clinical Science will also have individual study level responsibility for one or more trials.

Essential Duties and Responsibilities:

• Lead in the planning and execution of clinical studies to successfully move the program through pivotal trials and eventual submission, regulatory approval, and launch.

• Key clinical deliverables include document development (INDs, Protocols, IBs, applicable regulatory documents, etc.), medical and scientific input into the development of deliverables required for study activation and study conduct (CRFs, SAP, data listings, etc.), data review, and other deliverables as needed.

• May attend and contribute at meetings with Health Authorities (HAs) related to program; develop responses to HAs and IRBs on clinical/medical questions.

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