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Senior Software Engineer, Voice AI

Natera · US Remote · 2026-07-29

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About this role

Role Description

This is a high-autonomy, high-agency position for a voice AI engineer who thrives at the intersection of real-time systems, conversational AI, and healthcare. You'll own the architecture and delivery of Natera's Voice AI platform — a production system handling thousands of patient calls daily that provides automated test status, identity verification, billing support, and intelligent routing to human agents.

You'll work across the full voice AI stack: telephony, speech-to-text, LLM orchestration, text-to-speech, and analytics — building agentic conversational systems that directly improve patient access to their genetic testing results. This role requires deep understanding of the intricacies unique to voice AI: real-time audio streaming, turn-taking, interruption handling, latency optimization, and the orchestration challenges that distinguish voice from text-based AI systems.

Your work will span two critical domains:

1. Voice AI Platform Engineering

Design, build, and operate Natera's production voice AI system. This includes multi-agent orchestration, real-time WebSocket audio pipelines, telephony integration, and the voice-specific challenges of latency management, VAD tuning, barge-in handling, and ASR accuracy for medical terminology.

2. Agentic Conversational Architecture

Architect and implement autonomous agent workflows that handle complex patient interactions end-to-end — identity verification, OTP validation, personalized test status delivery, billing inquiries, and intelligent escalation. You'll design tool-calling patterns, agent handoff logic, state management across conversation turns, and the analytics infrastructure needed to measure and improve call efficacy.

What You'll Do


Own the end-to-end voice AI architecture — from Twilio media streams through LLM orchestration to TTS output and call disposition


Design and implement multi-agent systems using tool calling, agent handoffs, and shared conversation state for complex patient workflows


Build and optimize real-time audio pipelines — WebSocket streaming, codec handling (mulaw/PCM), VAD configuration, and interruption management


Architect analytics and observability infrastructure for voice-specific metrics: per-segment latency (STT/LLM/TTS), call efficacy, disposition accuracy, and ASR error rates


Solve voice-specific challenges: turn-taking timing, silence detection thresholds, barge-in recovery, medical term recognition, and end-to-end latency optimization


Integrate voice agents with internal services via secure authenticated APIs


Drive platform reliability — eliminate single points of failure, implement multi-provider LLM failover, and design graceful degradation paths


Collaborate with product and clinical operations to improve self-serve efficacy rates and reduce call escalations


Mentor team members on voice AI best practices and contribute to architectural decisions

What We're Looking For


5+ years of software engineering experience, with at least 2 years building production voice AI or conversational AI systems


Deep experience with voice AI pipelines — you understand the end-to-end flow from telephony through STT, LLM processing, TTS, and back to the caller, and you've solved real problems at each…

Skills asked for

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