Senior Manager, Stock Administration and Payroll

About this role

Eikon Therapeutics is a new biopharmaceutical company employing revolutionary technology at the intersection of chemistry, engineering, computation, and biology to discover novel treatments for life-threatening diseases. Eikon’s discovery platform is built on groundbreaking innovations from its founders (Nobel Prize, 2014), culminating in the creation of microscopes which enable real time, molecular-resolution measurements of protein movement in living cells, thereby unlocking otherwise intractable classes of proteins as drug targets.

Position Summary

Eikon Therapeutics is seeking a Senior Manager, Stock Administration and Payroll to lead and scale the company’s equity administration and payroll functions during a period of significant growth and increased regulatory complexity. This role will oversee all aspects of stock administration and payroll operations, ensuring accuracy, compliance, operational excellence, and a strong employee experience as the company continues operating as a public company.

The Senior Manager will partner closely with senior leadership across Finance, Legal, Total Rewards, HR Operations, People Team, and external vendors to drive compliant, scalable, and efficient processes across equity and payroll administration. This role requires a strategic, detail-oriented leader who can operate in ambiguity, balance hands-on execution with operational leadership, and build strong controls and infrastructure to support a growing organization.

About You

You are a strategic, battle-tested stock administration and payroll leader who thrives in complex, fast-moving environments. You bring deep expertise in equity programs and payroll operations and understand the importance of precision, controls, compliance, and employee experience — particularly as companies scale toward or operate as public entities. You are comfortable partnering with senior leaders, reconciling differing stakeholder perspectives, and guiding decisions that have lasting impact on employees and the organization. You balance hands-on execution with strategic oversight and enjoy building scalable processes, strengthening operational controls, and continuously improving how equity and payroll programs are administered and communicated.

What You’ll Do

• Lead end-to-end payroll processing and operations, ensuring timely, accurate, and compliant payroll administration, including bonuses, commissions, equity transactions, leave of absence, terminations, relocations, and other complex employee events

• Oversee the company's stock administration function, including administration of stock options, RSUs, ESPPs, and all equity lifecycle activities such as grants, vesting, exercises, releases, cancellations, and terminations

• Partner closely with Finance, HR Operations, Legal, and external vendors to ensure accurate data inputs, reconciliations, reporting, accounting treatment, and compliance with internal controls, SOX requirements, SEC regulations, tax laws, and company policies

• Perform and support stock-based compensation accounting and analyses under ASC 718, including forecasts, modifications, repricing activities, and equity pool tracking, utilization, and forecasting

• Prepare and maintain audit-ready documentation, governance materials, reporting, and controls supporting payroll and equity administration processes

• Partner with senior leadership to support compensation and equity strategy execution, including refresh grants, employee programs, and operational scaling initiatives

• Oversee relationships with payroll providers, stock administration vendors, transfer…