Senior Manager, Global Digital & Technology System Ownership

About this role

BeOne continues to grow at a rapid pace with challenging and exciting opportunities for experienced professionals. When considering candidates, we look for scientific and business professionals who are highly motivated, collaborative, and most importantly, share our passionate interest in fighting cancer.
BeOne is a global biopharmaceutical company dedicated to the discovery and development of innovative drug therapies for the treatment of cancer. At BeOne we believe that access to life-changing medicine sees no borders.
The Senior Manager, Global Digital & Technology System Ownership is accountable for the day-to-day ownership, operational health, lifecycle execution, and compliant management of Global Patient Safety R&D externally developed platforms and validated systems within the global R&D technology portfolio.
This role translates the GRDTS system ownership model into disciplined execution across technical configuration, platform operations, lifecycle planning, release and upgrade coordination, access management, documentation, security activities, vendor delivery, budget inputs, and inspection-ready evidence.
The Senior Manager partners with R&D business process owners, Global Technology Solutions, Information Security, Quality, vendors, Finance, Procurement, project teams, and support functions to ensure assigned platforms remain compliant, secure, reliable, supportable, and aligned with scientific and business needs.
The successful candidate brings strong regulated-systems experience specifically in Safety systems, hands-on operational leadership, structured problem solving, and the ability to coordinate global stakeholders through platform changes, incidents, competing priorities, and complex technical dependencies.
Essential Functions of the job:
System Ownership Execution & Governance
• Execute the system ownership model for Global Patient Safety’s externally developed platforms, maintaining clear accountability for business purposes, technical health, compliance posture, roadmap, support model, and lifecycle status.
• Maintain system governance routines, decision logs, ownership records, operating controls, documentation standards, and cross-functional action tracking for validated and non-validated platforms.
• Serve as the primary operational escalation point for assigned platforms, coordinating issue prioritization, risk review, lifecycle recommendations, and stakeholder alignment.
Technical Configuration, Platform Implementation, Upgrades & Integrations
• Lead and coordinate technical configuration, platform implementation, upgrade readiness, integration changes, environment preparation, testing support, release execution, and post-release stabilization for assigned platforms for Global Patient Safety such as Argus, Case Intake system, Signal Detection platform, and Safety data mart and etc.
• Ensure implementation and change plans align with Enterprise IT standards, cybersecurity requirements, validation expectations, business readiness, data and integration needs, and operational support models.
• Manage dependencies, risks, communications, cutover activities, vendor deliverables, and stabilization actions for upgrades, integrations, enhancements, and platform modernization efforts.
System Life-Cycle Management & Roadmap Execution
• Manage lifecycle activities for assigned systems, including onboarding, capability expansion, roadmap maintenance, technical debt reduction, modernization, retirement, and transition planning.
• Convert business needs, platform needs, functions, features, technical constraints, and compliance requirements into executable roadmap items and prioritized delivery plans.
• Coordinate feature and functionality additions, edits, and enhancements with business owners, technical teams, Enterprise IT, vendors, and Quality stakeholders.
Operational Excellence for Validated Systems
• Own execution and monitoring of validated-system operations, including user access workflows, role governance, audit trail review, periodic review, security checks, evidence collection, and remediation tracking.
• Ensure operating activities are consistently performed, documented, inspection-ready, and aligned with GxP, computer systems validation, 21 CFR Part 11, internal SOPs, and Quality expectations.
• Identify and implement improvements to operational controls, review cadence, exception management, metrics, and issue closure practices.
System Documentation & SOP Management
• Create, maintain, and periodically refresh system ownership artifacts, configuration records, technical operating procedures, administration and user access SOPs, support playbooks, and other system documentation.
• Ensure documentation reflects current configuration, access models, integrations, lifecycle status, change history, operating procedures, support arrangements, and inspection-readiness needs.
• Coordinate SOP creation, review, approval, training impacts, evidence readiness, and audit response activities with Quality, business process owners, and system teams.
System Security, Patch, Certificate & SSO Coordination
• Coordinate system security and maintenance activities, including patch planning, vulnerability remediation, certificate renewals, single sign-on coordination, identity and access dependencies, and risk-based prioritization.
• Partner with Enterprise IT and Information Security to plan and execute security actions in alignment with corporate policies, system criticality, business continuity needs, validation requirements, and change controls.
• Maintain visibility of security risks, exceptions, remediation owners, due dates, evidence, and closure status through appropriate governance and escalation channels.
Budget Support, AOP & Vendor Management
• Develop annual operating plan inputs for assigned platforms, including license, maintenance, upgrade, support, vendor, implementation, and lifecycle investment assumptions.
• Manage vendor operational performance, service…