Reporting Clinical Laboratory Scientist (RCLS)

About this role

A Rare Opportunity to Shape the Future of Genomics

Join a team of brilliant, passionate innovators determined to transform healthcare. At BillionToOne, we've built a category-defining, publicly traded company on Nasdaq where transparency fuels trust, collaboration drives breakthroughs, and every contribution moves the needle on our mission to make life-changing diagnostics accessible to all. We don't just aim for incremental improvements; we build products that are 10x better than anything that exists today.

Our scientists, engineers, sales executives, and visionaries are united by an unwavering commitment to changing the standard of care in prenatal and cancer diagnostics. This is where cutting-edge science meets human compassion, and every innovation you contribute helps remove the fear of the unknown from some of life's most critical medical moments.

If you're driven by purpose, energized by innovation, and ready to help shape the future of precision medicine at scale, this is where you belong.

The Prenatal Reporting Clinical Laboratory Scientist (RCLS) is responsible for performing high-complexity clinical laboratory data analysis, reviewing and interpreting molecular diagnostic and sequencing results, and ensuring the accuracy, reliability, and timely reporting of patient results in accordance with established laboratory procedures and applicable regulatory requirements.

The RCLS independently executes validated bioinformatics pipelines, evaluates analytical results and quality control metrics, troubleshoots, and reviews and releases clinical laboratory reports within established authorization and reporting procedures. For complex or unusual results requiring additional evaluation, the RCLS collaborates with Bioinformatics, the Laboratory Directors, and other appropriate clinical personnel to ensure accurate interpretation and reporting.

In addition to routine clinical reporting responsibilities, the RCLS is expected to demonstrate technical leadership by exercising sound scientific judgment, independently investigating complex analytical issues, providing technical guidance to colleagues, supporting personnel training, and identifying opportunities for continuous process improvement. The RCLS may also participate in additional technical leadership activities and cross-functional initiatives as assigned by laboratory leadership.

The RCLS collaborates closely with Laboratory Operations, Bioinformatics, Quality Assurance Management, Genetic Counselors, the Laboratory Directors and other cross-functional teams to support accurate clinical reporting, resolve technical challenges, and maintain efficient laboratory workflows.

The nature of this position requires exceptional attention to detail, strong analytical and problem-solving skills, excellent written and verbal communication, and the ability to manage multiple priorities in a fast-paced clinical laboratory environment. The successful candidate must demonstrate initiative, accountability, adaptability, and the ability to work both independently and collaboratively. This role is a hybrid work arrangement requiring approximately 60% on-site presence at the Union City and/or Menlo Park offices (three days per week on-site and two days per week remote).

Responsibilities:

Analysis and Reporting (70%)

Clinical Genomic Data Analysis and Interpretation

• Execute established and validated bioinformatics pipelines to process and analyze molecular diagnostic data from patient samples.

• Independently review and interpret clinical genomic data, including sequencing results, bioinformatics outputs, and associated quality control metrics, to ensure results meet established quality standards and reporting criteria.

• Identify, investigate, and troubleshoot analytical discrepancies, unusual findings, and potential data quality issues, collaborating with Bioinformatics and other appropriate technical teams to resolve complex issues as needed.

• Independently manage daily sample analysis priorities, monitor analytical workflows, and proactively communicate technical issues or concerns that may impact reporting accuracy or turnaround times.

Clinical Reporting and Quality Review

• Independently review, verify, and release clinical laboratory reports in accordance with established procedures, documented personnel authorization, and applicable regulatory requirements.

• Collaborate with other RCLSs, Bioinformatics, Genetic Counselors, Laboratory Directors, and other appropriate clinical personnel to evaluate complex findings, resolve reporting discrepancies, and obtain additional review or approval when necessary.

• Ensure the accuracy, completeness, and consistency of clinical reports while managing daily reporting priorities and maintaining established quality standards and turnaround time expectations.

• Maintain accurate documentation of analytical reviews, quality assessments, investigations, and reporting decisions in accordance with established laboratory procedures.

• Communicate reporting concerns and unresolved issues promptly to appropriate personnel, supporting continuity of reporting operations and timely resolution of sample-specific issues.

Technical Leadership, Quality Assurance, and Operational Support (30%)

Technical Leadership and Training

• Demonstrate initiative, accountability, and sound scientific judgment when performing clinical data analysis and reporting responsibilities.

• Independently investigate complex analytical discrepancies, troubleshoot technical issues, and identify appropriate solutions or escalation pathways.

• Serve as a technical resource for other Reporting CLS personnel by sharing knowledge, providing guidance, and supporting consistent application of established analytical and reporting procedures.

• Assist with training, onboarding, and mentoring Reporting CLS personnel and other clinical laboratory staff as appropriate.

• Promote technical competency, reporting consistency, and…