Principal Biostatistician Consultant - Remote (experience working with medical affairs and commercial)

About this role

Are you interested in working directly for a single sponsor while having the security and additional career opportunities that working for a global CRO can bring? Our team says it’s the best of both worlds….

ClinChoice is searching for an Principal Biostatistician Consultant to join one of our clients.

ClinChoice is a global full-service CRO with a strong focus on quality, professional development, and supportive culture. As a client-facing role, we are looking for confident candidates with the ability to work independently whilst establishing a high-trust environment with the client’s counterparts.

Position Description:

We are seeking an experienced Contract Biostatistician to support Medical Affairs and Real‑World Evidence (RWE) activities. The role will provide statistical leadership in the design, analysis, and interpretation of RWE/observational studies, external comparator analyses, and evidence generation strategies to support post‑marketing, payer, and hypothesis generation analysis. This position requires close collaboration with cross-functional teams including Medical, HEOR, Clinical Development, and Commercial.

Responsibilities and Duties:

• Partner with medical for publication strategies, HEOR or economic modeling inputs

• Provide statistical expertise in analyses using external control and/or synthetic control, meta-analyses, and causal inference analyses, e.g. propensity score matching method

• Contribute to manuscripts, abstracts and presentations

• Collaborate with HEOR to align analyses with HTA agency expectations

• Review protocols for real world evidence studies

• Work with statistical programmers to conduct ad hoc analyses; Conduct quality review of statistical analyses

• Perform statistical programming for advanced statistical methodologies and help statistical programmers QC their programs

• Review relevant medical literature

• Write statistical analysis plans

• Develop TLF shells and review programming specs

Minimum Requirements:

Experience: