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Executive Director, Health Economics & Outcomes Research (HEOR)

Travere Therapeutics · United States · 2026-10-22

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About this role

Department:
104275 FILSPARI Global StrategyLocation:
San Diego, USA- RemoteBe a part of a global team that is inspired to make a difference in the lives of people living with rare disease.
At Travere Therapeutics, we recognize that our exceptional employees are vital to our success. We are a dedicated team focused on meeting the unique needs of rare patients. Our work is rewarding – both professionally and personally – because we are making a difference. We are passionate about what we do.
We are seeking talented individuals who will thrive in our collaborative, diverse, fast-paced environment and share in our mission – to identify, develop and deliver life-changing therapies to people living with rare disease. We stick by our values centered on patients, courage, community, and collaboration to pursue our vision of becoming a leading biopharmaceutical company dedicated to the delivery of innovation and hope to patients in the global rare disease community.
At Travere Therapeutics, we are in rare for life. We continue to courageously forge new paths as we move toward a common goal of elevating science and service for rare patients.
Position Summary

The Executive Director, Health Economics & Outcomes Research (HEOR) will provide strategic leadership for the development and execution of health economics, outcomes research, real-world evidence, patient-reported outcomes and evidence synthesis strategies across Travere Therapeutics’ nephrology portfolio, including FILSPARI® (sparsentan), civorebrutinib, and future pipeline assets.
This individual will be responsible for developing an integrated evidence strategy that demonstrates the clinical, humanistic, and economic value of Travere’s therapies throughout the product lifecycle. The Executive Director will partner closely with Medical Affairs, Clinical Development, Market Access, Commercial, Regulatory Affairs, Biostatistics, and other cross-functional partners to identify evidence needs and ensure generation of high-quality data that supports scientific exchange, patient access, clinical development, and future value demonstration.
The Executive Director will serve as the senior HEOR expert for the Nephrology Franchise and will help shape the long-range evidence strategy for marketed and development-stage assets.
Responsibilities:

• Develop and lead the HEOR and value evidence strategy across Travere’s nephrology portfolio, including FILSPARI, civorebrutinib, and future pipeline assets.

• Develop integrated evidence-generation plans that address clinical, economic, humanistic, and healthcare decision-maker evidence needs across the product lifecycle.

• Partner closely with Clinical Development, Medical Affairs, Market Access, Regulatory, and Biostatistics to identify evidence gaps and ensure HEOR priorities are incorporated into broader asset and franchise strategies.

• Lead health economic research, including cost-effectiveness, budget impact, cost-of-illness, healthcare resource utilization, and other analyses that support understanding of the value of Travere therapies.

• Develop and execute real-world evidence studies leveraging existing data sources, including administrative claims, electronic medical records, registries, and other healthcare databases, to characterize disease burden, treatment patterns, patient journeys, healthcare resource utilization, and clinical outcomes.

• Lead the patient-reported outcomes strategy, including selection, development, validation, and incorporation of fit-for-purpose PRO measures into clinical development and evidence-generation programs where appropriate.

• Partner with Clinical Development to incorporate HEOR and outcomes research considerations early in development, including study design, endpoint strategy, evidence gaps, and future access needs.

• Identify opportunities to complement clinical trial evidence with epidemiology, real-world data, health economics, and patient-centered outcomes research.

• Develop evidence that supports payer and health technology assessment needs and contributes to value dossiers, reimbursement submissions, and other access-related evidence requirements.

• Anticipate future evidence needs and establish research plans that support new indications, lifecycle opportunities, and future nephrology assets.

• Partner with external research collaborations, data partners, research organizations, and other external experts.

• Develop and oversee HEOR publication plans and ensure timely dissemination of research through peer-reviewed publications, scientific congresses, and other appropriate scientific channels.

• Represent Travere externally with HEOR researchers, nephrology experts, academic collaborators, and other scientific stakeholders.

• Serve as an internal subject matter expert on health economics, outcomes research, real-world evidence, and patient-centered outcomes, providing strategic guidance to senior leadership and cross-functional teams.

• Manage external vendors, research partners, budgets, timelines, and project execution to ensure high-quality and timely delivery of HEOR initiatives.

• Ensure all activities are conducted in accordance with applicable laws, regulations, industry standards, company policies, and Travere compliance requirements.

Education/Experience Requirements:

• Advanced degree in health economics, outcomes research, epidemiology, public health, health services research, pharmacy, medicine, biostatistics, or a related discipline required; PhD, PharmD, MD, ScD, DrPH, or equivalent advanced degree strongly preferred.

• 12+ years of progressively responsible experience in HEOR, real-world evidence, outcomes research, market access evidence, or related disciplines within the biopharmaceutical industry, consulting, academia, or a combination thereof.

• Demonstrated experience developing and executing HEOR and evidence-generation strategies for marketed and/or development-stage assets.

• Strong experience using real-world…

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