Director, Employee Relations and Workplace Effectiveness
Amylyx · Cambridge, MA · 2026-09-04
About this role
Amylyx has an audacious mission to usher in a new era for treating diseases with high unmet needs. Where others see challenges, we see opportunities that we pursue with urgency, rigorous science, and unwavering commitment to the communities we serve. We are a clinical-stage company currently focused on post-bariatric hypoglycemia (PBH), Wolfram syndrome, and amyotrophic lateral sclerosis (ALS).
Our mission is powered by our people. Our core values – be audacious, be curious, be authentic, be engaged, and be accountable – creating a culture of caring. Amylyx has assembled an experienced team ready to take action because the communities we serve have no time to wait. If you share our passion and are determined to tackle some of medicine’s toughest problems, we encourage you to read the opportunity below and apply.
The Opportunity
The Director, Employee Relations and Workplace Effectiveness is responsible for supporting a positive, productive, inclusive, and compliant workplace by providing expertise across employee relations, workplace investigations, performance management, manager coaching, and organizational effectiveness. Serving as a key partner to the HR Business Partner team, this role will provide consultation and hands-on support for complex employee matters, helping ensure consistent, thoughtful, and legally compliant practices across the organization. This person will also identify trends and opportunities across employee relations activities and translate those insights into proactive manager education, tools, policies, and workplace practices.
Responsibilities
Employee Relations & Workplace Investigations
• Serve as a subject matter expert for employee relations matters, partnering closely with HR Business Partners on complex or sensitive employee situations.
• Lead and/or support workplace investigations involving employee complaints, conduct concerns, discrimination, harassment, retaliation, workplace behavior, and other policy matters.
• Conduct objective, thorough, and timely investigations, including interviews, documentation review, findings, and recommendations.
• Provide guidance regarding corrective action, performance concerns, conflict resolution, and employment decisions.
• Ensure appropriate documentation and consistency in the handling of employee relations matters.
• Partner with Legal and HR leadership on matters presenting heightened employment, compliance, or organizational risk
Manager Coaching & Performance Management
• Provide managers and HR Business Partners with practical guidance on performance management, accountability, communication, conflict resolution, and difficult employee conversations.
• Support the development and review of performance improvement plans, written warnings, corrective actions, and other performance documentation.
• Help managers distinguish between performance, conduct, capability, and workplace relationship issues and determine appropriate interventions.
• Build manager capability so that routine employee matters can be effectively addressed at the manager and HRBP level while appropriately escalating higher-risk situations.
Workplace Effectiveness & Culture
• Partner with HR Business Partners and HR leadership to identify opportunities to strengthen team effectiveness, employee engagement, communication, and retention.
• Identify recurring workplace themes and organizational pain points and recommend proactive solutions.
• Support interventions for teams experiencing conflict, leadership challenges, communication breakdowns, or other workplace effectiveness concerns.
• Partner across HR on initiatives designed to strengthen manager effectiveness and the overall employee experience.
Compliance & Policy Management
• Help ensure employment practices are consistent with applicable federal, state, and local employment laws and company policies.
• Maintain and enhance employee relations policies, guidelines, templates, and manager resources.
• Partner with Legal on policy development and employment-related risk mitigation.
• Support consistent application and interpretation of HR policies across the organization.
• Remain current on evolving employment practices and regulatory requirements and translate changes into practical guidance for HR and managers
Training & Manager Education
• Partner with Learning and Organizational Development to develop and deliver training and resources for managers and employees on topics such as performance management, respectful workplace practices, effective feedback, conflict resolution, investigations, and employee relations fundamentals.
• Identify training needs based on employee relations trends and recurring manager challenges.
• Partner with HR colleagues to incorporate employee relations learnings into broader manager and leadership development programs.
Organizational Insights & Reporting
• Establish meaningful tracking and reporting of employee relations matters, including case types, outcomes, recurring themes, and organizational trends.
• Analyze employee feedback, turnover, exit interview information, employee relations cases, and other workforce data to identify emerging risks or opportunities.
• Provide HR leadership and HR Business Partners with actionable insights and recommendations.
• Use trends and case learnings to inform policies, manager education, organizational interventions, and broader people strategies.
Required Qualifications
• Bachelor’s degree and 10+ years of progressive Human Resources experience supporting employee relations, investigations, and performance management; equivalent relevant professional experience will also be considered in lieu of education requirements.
• Demonstrated experience independently conducting and documenting complex workplace investigations.
• Ability to travel as needed to conduct investigations.
• Strong working knowledge of U.S. employment laws and HR/employee relations best practices;…
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