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Business Performance Director

Amgen · United States · 2026-10-22

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About this role

Career Category
Business DevelopmentJob Description
Join Amgen’s Mission of Serving Patients
At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.
Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. Amgen is advancing a broad and deep pipeline and portfolio of medicines to treat heart disease, obesity and obesity-related conditions, rare diseases, inflammatory conditions and cancer. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.
Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Business Performance Director

What you will do

Let’s do this. Let’s change the world. In this vital role you will build business cases for approval by senior executives, independently develop transformation strategies for key initiatives, and lead initiatives through the transformation process. This will include developing value realization measures, managing the value realization process, and determining the best use of transformation tools and methods to help initiatives achieve intended outcomes.
Candidate should have experience leading change management for large business transformation programs and initiatives. They will develop and implement complex change management strategies and plans related to changes to organizational structures, processes, and technologies across multiple timeframes and impact. This requires expertise in sponsorship development, change communications, capability development, and behavior change. Must be able to oversee others execution of associated tactics.
This role will lead senior leaders and teams through structured problem solving using Disciplined Approach methodology to drive alignment around critical issues, options, and solutions. These problems will often be cross functional in nature. They will be a thought partner for leaders and work across technology, process, and business to support solution implementation.
Will be accountable for independently delivering the following:

• Effective executive level business cases, including financial analysis

• Establishing initiative governance with senior leaders

• Change team management and facilitation

• Interdependency identification and management

• Establish realization measures and targets

• Develop and manage value realization plan

• Assess and mitigate risks to delivery and value realization

• Identify impacted populations and expected level of disruption

Fully Remote with onsite presence required for critical workshops and planning sessions.
Responsibilities:

• Maintain 12 quarter plan for initiatives and programs

• Integrate key activities and milestones across initiatives

• Maintain measures that track progress and can be used in communications with Executives

• Develop and manage “key milestone readiness” and “release readiness” processes for all initiatives

• Lead the end-to-end organizational change management for transformation programs, integrating change strategy, stakeholder engagement, communications, and training to drive adoption and sustained performance.

• Design and execute integrated change management plans spanning process, technology, workforce, risk, and communications to drive clarity and coordinated execution.

• Develop and execute capability frameworks that clarify roles, expectations, and leadership readiness to support successful operating model adoption.

• Establish governance and oversee delivery of role-based learning and training programs, ensuring alignment to transformation priorities and role requirements.

• Manage internal and external partners to deliver scalable, high-quality learning experiences, including oversight of scope, deliverables, quality, and timing.

• Establish structured communications strategies and engagement rhythms to enable transparency, alignment, and stakeholder commitment throughout the transformation lifecycle.

• Monitor and report capability building, training, and change metrics to inform leadership decisions and continuously improve the change approach.

• Standardize and scale capability enablement processes to ensure consistency, efficiency, and sustainability across the organization.

What we expect of you
We are all different, yet we all use our unique contributions to serve patients. The strategic and transformational leader we seek is an experienced business performance professional with the following qualifications.

Basic Qualifications:
Doctorate degree and 4 years of Business Transformation, Organizational Change Management, Strategic Planning, or Program Management experience
OR
Master’s degree and 7 years Business Transformation, Organizational Change Management, Strategic Planning, or Program Management experience
OR
Bachelor’s degree and 9 years of Business Transformation, Organizational Change Management, Strategic Planning, or Program Management experience

Preferred Qualifications:

• Strong transformation skillset

• Financial acumen

• Project management skills

• Strong organizational skills, including ability to follow assignments through to completion

• Collaborate and communicate with initiative leadership teams

• Strong communication (both written and oral), facilitation, and presentation skills

• Strong skill in working independently and to effectively interact with various levels

• Demonstrate the Amgen Values and Leadership Characteristics

• Experience operating in regulated, quality-sensitive environments (biopharma preferred) with understanding of transformation delivery…

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